Mayo Clinic vs Cognitive FX for Post-Concussion Symptoms
Mayo Clinic treats about 1,500 people with concussion each year, and all of its campuses offer concussion care.1,2 For symptoms that last more than three months, which Mayo calls persistent...
Published peer-reviewed research shows that Cognitive FX treatment leads to meaningful symptom reduction in post-concussion symptoms for 77% of study participants. Cognitive FX is the only PCS clinic with third-party validated treatment outcomes.
READ FULL STUDY
Amen Clinics does not list a price for its evaluation. Its pricing page says cost varies with the services recommended.1 In 2024, our team was quoted $5,300 for a full evaluation with two SPECT scans, and pricing may have changed since then. Amen offers a free call with its advisors and an optional $230 consultation that is credited toward the evaluation, and it asks for a $500 to $1,500 deposit.2,3 Cognitive FX, a concussion rehabilitation clinic in Provo, Utah, lists its prices: scans are $1,500 and a week of treatment is $13,000. Cognitive FX is not affiliated with Amen Clinics.
Amen Clinics now quotes each patient individually and offers a personalized estimate on request.1 Here is what each clinic lists or what we could confirm, side by side.
Cost side by side
What you pay at each clinic
| Amen Clinics | Cognitive FX | |
|---|---|---|
| First step | Free call with an Amen advisor, or an optional $230 consultation with a nurse practitioner, applied toward the evaluation3 | Short online questionnaire and consult call: free |
| Deposit | $500 to $1,500, depending on the evaluation2 | None listed |
| Evaluation or scan | Not listed. Our team was quoted $5,300 in 2024 for a full evaluation with two SPECT scans; pricing may have changed. A 2021 article reported about $4,000 in 20205 | fNCI scan: $1,500, credited toward treatment if you continue |
| What the evaluation includes | Two SPECT scans, psychological and cognitive testing, a clinical history, a physician meeting, follow-ups and coaching, about 10 hours of care1,4 | One week of treatment: $13,000, with both scans included. Two weeks: $24,700 |
| Ongoing treatment | Recommended after the evaluation: therapy, neurofeedback, HBOT, supplements or medication management. Ask Amen for pricing | Home program and video follow-ups for about 2 to 3 months after your week |
| Insurance | Does not bill insurance. Walk-out statement for possible out-of-network reimbursement4 | Out-of-network. Superbill for possible reimbursement |
| Payment options | CareCredit, HSA and FSA1 | CareCredit, HSA and FSA |
Amen Clinics details from amenclinics.com, checked October 22, 2026. The $5,300 figure is a 2024 quote and may have changed. Cognitive FX prices as of October 2026.
The two clinics are closer on cost than they first look. Neither bills insurance, both accept CareCredit, HSA and FSA, and both give you paperwork to seek out-of-network reimbursement. The main difference is what the price covers. An Amen evaluation pays for testing, scans, a treatment plan and follow-up visits. A Cognitive FX week pays for the scans and a full week of therapy.
Services side by side
Testing, therapies and medical care
Amen Clinics from its own website. Cognitive FX from our clinical team.
Service
Amen Clinics
Cognitive FX
Testing and imaging
SPECT brain scanBlood flow at rest and during a task
Functional MRI scan (fNCI)Brain activity during thinking tasks
Standard MRIShows brain structure
Neuropsychological testingThinking, memory and mood
qEEG brain mappingElectrical activity
Therapies
Vestibular and vision therapyDizziness, balance and eye problems
Cognitive and occupational therapyMemory, attention, daily tasks
Exercise and neuromuscular therapyGraded exercise, neck and posture
Counseling and psychotherapyAnxiety, mood and coping
NeurofeedbackBrainwave training
Hyperbaric oxygen (HBOT)Pressurized oxygen sessions
Medical care and billing
Prescription medicationMedication management
SupplementsFrom BrainMD, Dr. Amen's supplement company
Insurance billingClinic bills your health plan
Amen Clinics from its services, concussion and method pages, checked October 22, 2026.7,8,11 Amen also lists Interactive Metronome training and Irlen screening for light sensitivity. "Not listed" means the clinic does not list it, not that it can never arrange it.
The two clinics come at brain injury from different directions. Amen Clinics is a psychiatric practice with 11 locations.6 Its concussion program pairs SPECT imaging with hyperbaric oxygen, neurofeedback, hormone evaluation and nutritional supplements, alongside psychiatric care, therapy and medication management.7 Cognitive FX is a rehabilitation clinic. Its program is built around therapies that retrain the systems a concussion can disrupt: vestibular and vision therapy, cognitive and occupational therapy, graded exercise and neuromuscular work, with counseling as needed.
Both use functional brain imaging, both see patients with lingering symptoms after a head injury, and both treat mood symptoms when they are part of the picture.
Amen Clinics may be the better fit if:
Cognitive FX may be the better fit if:
If you are looking at Amen Clinics mainly for depression, we also offer fMRI-guided TMS for depression.
Is this you?
Signs our program may fit
If two or more sound like you, a free consult is the next step.
Book my free consultThis list is not a diagnosis.
Both scans look at how the brain works rather than only its structure, and they measure it in different ways.
Amen Clinics uses SPECT, which tracks blood flow in the brain with a small injected tracer. You have two scans on separate days, one at rest and one during a concentration task, each taking about 20 minutes.4 Amen uses the scans with your history, psychological and cognitive testing and lab tests when needed.7
Cognitive FX uses fNCI, a functional MRI that measures how 56 brain regions work while you do thinking tasks and compares them with a healthy reference group. MRI does not use a tracer or radiation. The scan is not a diagnosis on its own. We use it with your history and other tests to decide which therapies you need, and we repeat it at the end of your treatment week.
The 3D model below shows what an fNCI scan measures, using sample results on a model brain. Red shows regions working harder than a healthy reference group and blue shows regions working less. Drag or swipe to rotate it, and switch between the sample patients. It is an illustration, not your scan or a diagnosis.
Most treatments target symptoms. Ours targets the source — the specific brain regions that aren’t working the way they should.
At Amen Clinics, the evaluation takes two to three days, about two to three hours each day.4 Your physician then builds a plan, with follow-ups at about one week, two to four weeks, 30 days, 90 days and six months, and an option to repeat the SPECT scan.8 Most follow-ups and medication management happen by telehealth.8 Treatment may include psychiatry visits, therapy, neurofeedback, hyperbaric oxygen at select locations and supplements from BrainMD, Dr. Amen's supplement company.8
At Cognitive FX, treatment happens in one intensive week in Provo. You spend full days at our clinic, about 9 to 5, moving through therapies in a cycle of exercise, targeted therapy and rest. Every therapist works from the same scan report and checks in with the rest of the team at the end of each day. The week is demanding, and many patients feel more tired while it is underway.
Your week at Cognitive FX
One intensive week in Provo

Dr. Alina K. Fong, PhDClinical Director

Dr. Lynn M. Gaufin, MDDirector of Neurosurgery

Annie Morgan, RNDirector of Patient Care
Plus other therapists as needed. Meet the full team
Amen Clinics reports that 81.3% of fully compliant patients with a traumatic brain injury said they improved after six months, based on patient follow-up surveys.9
For Cognitive FX, an independent study by Amsterdam UMC and UMC Groningen found that 77% of the 52 patients measured six months after treatment had a clinically meaningful reduction in symptoms.10 The study was observational, not randomized, and individual results vary. Read our summary of the independent study.
Next steps
Book a free consult about your symptoms
Prefer to call? (385) 375-8590, 9 to 5 Mountain.
Related reading: UPMC vs Cognitive FX and Mayo Clinic post-concussion care.
Amen Clinics does not list a price. Its pricing page says cost varies with the services recommended. In 2024, our team was quoted $5,300 for a full evaluation with two SPECT scans, and pricing may have changed since then. A 2021 peer-reviewed article reported about $4,000 for an initial SPECT evaluation in 2020.
Amen Clinics does not bill insurance. It gives patients a walk-out statement with diagnosis and billing codes that they can submit for possible out-of-network reimbursement. Cognitive FX works the same way: we are out-of-network and give you a superbill.
They are priced differently. At Cognitive FX, scans are $1,500 and a week of treatment is $13,000, with both scans included. An Amen evaluation covers testing, scans and follow-up visits. Amen's site does not list prices for ongoing treatment such as neurofeedback or HBOT. Ask each clinic for a written estimate for your situation.
Yes. Amen Clinics runs a Concussion Rescue Program that combines SPECT imaging, history and testing with treatments such as hyperbaric oxygen therapy, neurofeedback, hormone evaluation and nutritional supplements.
Amen Clinics reports that 81.3% of fully compliant patients with a traumatic brain injury said they improved after six months. The figure comes from patient follow-up surveys, and Amen does not cite a peer-reviewed study for it.
Yes. Our program works alongside your neurologist or primary care doctor and does not replace their follow-up.
In an emergency, call 911.
Dr. Mark D. Allen holds a Ph.D. in Cognitive Science from Johns Hopkins University and received post-doctoral training in Cognitive Neuroscience and Functional Neuroimaging at the University of Washington. As a co-founder of Cognitive Fx, he played a pivotal role in establishing the unique and exceptional treatment approach. Dr. Allen is renowned for his pioneering work in adapting fMRI for clinical use. His contributions encompass neuroimaging biomarkers development for post-concussion diagnosis and innovative research into the pathophysiology of chronic post-concussion symptoms. He's conducted over 10,000 individualized fMRI patient assessments and crafted a high-intensity interval training program for neuronal and cerebrovascular recovery. Dr. Allen has also co-engineered a machine learning-based neuroanatomical discovery tool and advanced fMRI analysis techniques, ensuring more reliable analysis for concussion patients.
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Published peer-reviewed research shows that Cognitive FX treatment leads to meaningful symptom reduction in post-concussion symptoms for 77% of study participants. Cognitive FX is the only PCS clinic with third-party validated treatment outcomes.
READ FULL STUDY